June 25, 2020January 29, 2023 SARM education

What is MK 677 or Ibutamoren?

TL;DR: MK 677 is an extremely popular compound used as replacement for regular HGH injections. It is not as powerful as elevated doses of Human Growth Hormone, but it is way cheaper, very bioavailable and our MK 677 has incredibly purity.

Half-life: 24 hours

Dose: 10-25 mg/day.

Cycle Length: 8 to 16 weeks

PCT: Never

Benefits

Muscle:

Even though Ibutamoren will increase IGF-1, one of the most anabolic hormones in our bodies, it will not accrue a significant amount of muscle mass on its own.

It will, however, amplify the effects of actual anabolics like SARMs or steroids if you choose to stack it with those. Furthermore, Ibutamoren has been proven to be anti-catabolic, so it will help preserve muscle on a caloric deficit.

Growth Hormone (and thus Ibutamoren) helps everything work better, but it will not add much muscle on its own.

Strength and performance:

Ibutamoren is known for increasing water retention, which often helps improve strength. The positive effect of high HGH on the joints and tendons will also help you become stronger and perform better.

Fat loss:

Growth Hormone is known for boosting fat loss, so Ibutamoren will indeed help you burn fat. Unfortunately, it will make you a lot hungrier, so not overeating may prove to be difficult and it could stop you from losing weight.

Bones and joints:

As previously mentioned, having elevated levels of Growth Hormone will not only strengthen bones, but it will also heal, repair, and strengthen your joints, ligaments and tendons. For this reason, one will be less likely to get injured in the gym.

Many people claim that Ibutamoren has fixed chronic pain in some areas of their body, and it will definitely boost the speed at which your body heals itself (whether it be skin damage, skin burns, bone fractures, injured joints, etc…)

Recovery:

Since HGH speeds up tissue healing and regeneration, one can expect faster muscle recovery when taking Ibutamoren. This means you will feel less sore and you will be read to work out again sooner.

Increased Hunger:

This can be an undesired side-effect of Ibutamoren but being more hungry during a bulk will help you eat enough to keep growing. Bodybuilders who struggle to gain weight due to lack of hunger can benefit greatly from this property.

Some users report no extra hunger when they take Ibutamoren before bed, so if you want to benefit from the increased hunger, take Ibutamoren first thing in the morning.

Better sleep:

One of the best things about Ibutamoren is that it makes sleep better. It causes deeper and longer REM sleep and helps you feel more refreshed and energized the next day.

According to some people, 6 hours of sleep on Ibutamoren are as effective, refreshing and energizing as 8 hours of normal sleep.

Another great thing about better sleep is that it will help you recover faster and gain more muscle in the long run, as well as improve your hormonal levels.

Nutrient partitioning:

Ibutamoren will make nutrient partitioning more efficient, meaning that carbs, protein and fat will be used more effectively. In other words, if you are bulking up you will gain less fat than your otherwise would.

Cosmetic benefits:

The added water retention helps fill out the muscles and makes them look bigger. Gains of up to 10lbs in water retention are possible. Unfortunately, the drawback of water retention is that you will look puffy and bloated, but if you are already very lean, the extra water weight can make you look fuller and more pumped. Having extra growth hormone will also make your skin and hair look younger and healthier.

Side-effects

Water retention

Even though the water retention can be useful when it comes to looking bigger, getting stronger and protecting your joints, it is an undesired effect for some people

Firstly, it can make your muscles blurry and less defined if you are not extremely lean to begin with, and it will make your face chubby and round, therefore making you less attractive.

Secondly, if the water retention becomes too heavy (due to taking a very high dose or eating insane amounts of carbs), it can have a negative impact on the joints.

And finally, excessive water retention can cause high blood pressure

Lethargy:

Some users report feeling lethargic throughout the day if they take more than 15mg/day.

Side-effects

The increased hunger be a negative side-effect for those who are trying to lose weight. Fortunately, it can be mitigated by taking the compound before bed instead of taking it in the morning.

Another possible side-effect of Ibutamoren is growth of hands, feet, nose and other parts of the body due to having elevated levels of Growth Hormone, but one would have to take Ibutamoren for years on end for that to happen.

DATASHEET FOR MK 677, Ibutamoren

Advancedresearch.bio Purity: 98.4%

Dosage: 25mg/mL ±10%

Application: Non-peptide ghrelin receptor agonist

CAS: 159752-10-0

Molar Mass: 528.662 g/mol

Chemical Formula: C₂₇H₃₆N₄O₅S

IUPAC Name: 2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4′-piperidine]-1′-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide;methanesulfonic acid

Synonyms:Ibutamoren, MK-677, MK-0677, MK677, L-163,191, L163191, Nutrobal

Storage: Room temperature

Solubility: Water, Ethanol, PEG400

Physical Form: Ibutamoren Mesylate salt solved in PEG400